Podiatrists

Indicated for neuroischaemic and neuropathic ulcers, OXYZYME and IODOZYME wound dressings are as easy to use as conventional dressings and are comfortable for the patient.

Both dressings use advanced chemistry to work like a molecular pump, drawing in oxygen from the atmosphere and releasing iodine to the surface of the wound. Being indicated for infected wounds, IODOZYME releases a relatively higher amount of iodine than OXYZYME. Oxygen has been used to aid wound healing for a number of years, primarily through Hyperbaric Oxygen Therapy (HBO).

However for various reasons it has not been widely adopted. Meta-analysis of the case study programme featuring diabetic foot ulcers indicates a positive clinical response to the use of OXYZYME: Diabetic foot ulcers (n=13) Healed/Improved was 77% at 6 weeks, with previous dressing regimes having included Aquacel, Aquacel Ag, Biatain, Mepilex, Versiva XC, Honey, and VAC (All brands are trademarks of their respective owners).

“Clinical experience with adjunctive hyperbaric oxygen therapy in the treatment of diabetic ulcers has shown wound granulation tissue formation and accelerates wound contraction and secondary closure. In addition to wound hyperoxia, increased wound nitric oxide production caused by hyperbaric oxygen therapy also appears to be important for successful diabetic wound repair.” 1

“Hyperbaric oxygen enhanced the healing of ischaemic, non-healing diabetic leg ulcers and may be used as a valuable adjunct to conventional therapy when reconstructive surgery is not possible.” 2

1. Boykin JV, “The nitric oxide connection: hyperbaric oxygen therapy, becaplermin, and diabetic ulcer management”, Adv. Skin Wound Care, 2000;13(4 Pt 1):169-174

2. Abidia A, Laden G, Kuhan G, Johnson BF, Wilkinson AR, et al., “The role of hyperbaric oxygen therapy in ischaemic diabetic lower extremity ulcers: a double-blind randomised controlled trial”, Eur. J. Vasc. Endovasc. Surg., 2003; 25(6):513-8.